"Go out in the world and fuck it up beautifully" --John Waters
https:/
@swissmiss And finally a great video with some excellent history/background/motivation: https:/
@campbellcate I like your general intention here, but half the video is reinforcing the painfully negative stereotypes before you get to any empowerment message... Why not simply start with the empowerment and proceed from there?
#40031 (Consider Adding Web Annotations to WordPress) – WordPress Trac https:/
Mostly to provide some additional resources to the conversation I'll add the following:
Web Annotation Working Group's [https:/
Prior to the WPTavern post which motivated the conversation, there was a [https:/
Keep in mind that some of the standard is geared specifically toward browsers and browser vendors, though WordPress could certainly implement some of the pieces from the CMS side.
Jeremy, no worries, it's not openly transparent unless you look at the html source of the page directly. WordPress has a nifty feature that if you add an .mp3 URL to the text field, it will automatically format it as a player (much like embedding a youtube video), in my case I used an <audio> element wrapped around a .mp3 URL which creates a slightly different player (based on the web browser implementation of the spec) with somewhat different functionality.
As for replying to multiple sites at once on Known, on a "reply" post you'll have one URL in a field by itself, then you can click on the "Reply to a site" link under the "New Status Update" box to add another box, and so on. Thus, this particular post will send three replies. One to your response about the media player, one to your question about multiple replies, and a third which I'm sending to my original post which preceded your reply, so that it contains a full chain of the replies. There's also a "Remove URL" link in case you add too many--I don't think the post will publish if you have empty reply fields.
If you look on the wiki, there's a thing called salmentions (salmon+webmention) which programatically checks all the replies to replies and syndicates one's response everywhere so that all the posts in a chain of conversation get webmentions to have a complete record of a conversation. Few sites do this yet in practice, but if you're diligent on Known, you can effect salmentions manually.
Jeremy, this seemed a little long for Loqi to handle, and seemed worth keeping for later, so my response is below:
I understand your situation and have been following some of the discussion about content ownership and reposting. I'm all about giving credit where it's due, and bend over backwards (as far as I'm technically able) to do so. (Wait until you see some of the chicanery I'm trying to pull of for simple bookmark posts...)
It's for that reason that I provided a direct link to the podcast itself in the post as well as a blockquote synopsis in an effort to advertise on your show's behalf. Embedding the mp3 directly on my page was done as a means of helping people easily "sample" the podcast to get them hooked, in which case they would need to subscribe directly to the source. (I also did it to make it easier for me to relisten to it later if I like.) I'm still trying to get Twitter Player Cards to work properly so that could be an additional avenue for sampling on POSSE copies.
Additionally, by embedding the mp3 (I could have scraped it and then hosted it myself, but really, what's the point of that? unless I really wanted to steal it and run advertising against it for myself), your hosting server gets pinged for the "listen" or for any potential downloads because it's being served directly from your site (and not mine), which presumably most podcasters are tracking for advertising purposes. (YouTube and other video hosters do this for embedded videos.)
What I did was not much different than what Huffduffer is doing in bookmarking audio from your podcast on its site. Huffduffer isn't hosting a separate audio file itself, it's hosting a pointer to your file on its site and also syndicating it via RSS and/or Apple iTunes to others who will ultimately stream it or download it directly from your server. In fact, given this, I'm just acting like a mini-Apple iTunes without as much functionality, but I'm only advertising your podcast and not hundreds of thousands of others.
If you did have sponsors, you would presumably also give them airtime in your podcast which would then be heard as well, and tracked by your own server as a stream start or download. I suspect if you had visual advertising on your site, I could/might also embed that so you get a ping for the page load on my site as well. :)
If you're not aware or need it for clients, WordPress gives you the ability to customize your site's ability to provide oEmbeds, so with/for advertisers, you could add text, media, and even a visual advertisement to the pages for your audio podcasts. Other WordPress sites (or sites that consume oEmbed data) that include your URL in their pages then re-render it as a "player card" which presumably pings your server with a "hit" thus giving you credit for the work. Here's an example of an oEmbed for another WordPress site at the top of this post: http:/
Perhaps I'm mistaken about the process, and you may be far more knowledgeable than I given your experience in the space, but I'm pretty sure that by embedding and not copying and hosting it myself, you should be able to garner the lion's share of the credit while I'm just serving as free advertising on your behalf.
As an alternate example, things are somewhat different in Marty's case of creating a separate piece of audio and copying and embedding it into his podcast as aaronpk's music didn't register a ping of any sort (other than possibly a webmention which only happened once), so aaronpk couldn't have monetized his audio the way you could have with a sponsored podcast.
@eatpodcast @jimpick @realkimhansen @abrams @Feedly Jeremy, I agree with you wholeheartedly that SoundCloud is a dreadful option overall--apologies if I gave the impression otherwise. Given it's cost and the fact that it's what I would call a super-silo make it a non-starter unless you're looking for a very sort term solution or if you're a mega-media company and have the money to burn to try to reach another tiny sliver of audience you didn't have before.
Sadly, given their position in the space, companies like Apple, SoundCloud, and perhaps a few others haven't continued building out and innovating. (Marco Arment, who you mentioned in this particular podcast, recently had an episode on being "Sherlocked" that touches on the economics of perhaps why they haven't gone the extra mile http:/
We also need a better/easier solution for the average Jane who wants to create a simple podcast without spending two weeks doing a mini-startup to set it all up and get it going with the widest distribution possible.
I'm honestly puzzled that YouTube doesn't get into the space as they've already got a huge piece of the puzzle built. Just provide the ability to strip out an .mp3 file from a video (there's a huffduffer bookmarklet that allows this: http:/
I do appreciate larger companies like This American Life doing things like Shortcut [https:/
As an aside, I've just noticed at http:/
OK Go’s new video for “The One Moment” is a stunning example of high-speed video. https:/
@TMWestervelt If you want, I think I may have gotten the audio from that section at http:/
Real-time MRI for precise and predictable intra-arterial stem cell delivery to the central nervous system
An MRI shows stem cells labeled with iron oxide nanoparticles being injected into an animal’s brain. Click to view video. (Credit: Piotr Walczak/Johns Hopkins Medicine)
Working with animals, a team of scientists reports it has delivered stem cells to the brain with unprecedented precision by threading a catheter through an artery and infusing the cells under real-time MRI guidance.
In a description of the work, published online Sept. 12 in the Journal of Cerebral Blood Flow and Metabolism, they express hope that the tests in anesthetized dogs and pigs are a step toward human trials of a technique to treat Parkinson’s disease, stroke, and other brain damaging disorders.
“Although stem cell-based therapies seem very promising, we’ve seen many clinical trials fail. In our view, what’s needed are tools to precisely target and deliver stem cells to larger areas of the brain,” says Piotr Walczak, M.D., Ph.D., associate professor of radiology at the Johns Hopkins University School of Medicine’s Institute for Cell Engineering. The therapeutic promise of human stem cells is derived from their ability to develop into any kind of cell and, in theory, regenerate injured or diseased tissues ranging from the insulin-making islet cells of the pancreas that are lost in type 1 diabetes to the dopamine-producing brain cells that die off in Parkinson’s disease.
Ten years ago, Shinya Yamanaka’s research group in Japan raised hopes further when it developed a technique for “resetting” mature cells, such as skin cells, to become so-called induced pluripotent stem cells. That gave researchers an alternative to embryonic stem cells that could allow the creation of therapeutic stem cells that matched the genetic makeup of each patient, greatly reducing the chances of cell rejection after they were infused or transplanted. But while induced pluripotent stem cells have enabled great strides forward in research, Walczak says they are not yet approved for any treatment, and barriers to success remain.
In a bid to address once such barrier – how to get the cells exactly where needed and no place else – Walczak and his colleague Miroslaw Janowski, M.D., Ph.D., assistant professor of radiology, sought a way around strategies that require physicians to puncture patients’ skulls or inject them intravenously. The former, Walczak says, is not only unpleasant, but also only allows delivery of stem cells to one limited place in the brain. In contrast, injecting cells intravenously scatters the cells throughout the body, with few likely to land where they’re most needed, says Walczak.
“Our idea was to do something in between,” says Janowski, using intra-arterial injection, which involves threading a catheter, or hollow tube, into a blood vessel, usually in a leg, and guiding it to a vessel in a hard-to-reach spot like the brain. The technique currently is used mainly to repair large vessels in the brain, says Janowski, but the research team hoped it might also be used to get stem cells to the exact place where they were needed. To do that, they would need a way of monitoring the catheter placement and movement of implanted cells in real time.
Walczak and Janowski teamed with colleagues including Monica Pearl, M.D., an associate professor of radiology practicing in the Division of Interventional Neuroradiology, who specializes in intra-arterial procedures. Usually the procedure is performed using an X-ray image as a guide, but that approach ruled out watching injected stem cells’ movements and making adjustments in real time.
In their experiments, after placing the catheter under X-ray guidance, they transferred anesthetized dog and pig subjects to an MRI machine, where images were taken every few seconds throughout the procedure. Once the catheter was in the brain, Pearl pre-injected small amounts of a harmless contrast agent that included iron oxide and could be detected on the MRI. “By using MRI to see in real time where the contrast agent went, we could predict where injected stem cells would go and make adjustments to the catheter placement, if needed,” says Janowski. Adds Jeff Bulte, Ph.D., a professor of radiology who participated in the study, “It’s like having GPS guidance in your car to help you stay on the right route, instead of only finding out you’re lost when you arrive at the wrong place.”
The team then injected both small stem cells (glial progenitor cells from the brain) and large mesenchymal stem cells from bone marrow into the animals under MRI, and found that in both cases, the pre-injected contrast agent and MRI allowed them to accurately predict where the cells would end up. They could also tell whether clumps of cells were forming in arteries and, if so, possibly intervene to avoid letting the clumps grow large enough to cut off blood flow and pose a danger. “If further research confirms our progress, we think this procedure could be a big step forward in precision medicine, allowing doctors to deliver stem cells or medications exactly where they’re needed for each patient,” says Walczak. The research team is planning to test the procedure in animals as a treatment for stroke and cancer, delivering both medications and stem cells while the catheter is in place.
Other authors on the paper are Joanna Wojtkiewicz, Aleksandra Habich, Piotr Holak, Zbigniew Adamiak and Wojciech Maksymowicz of the University of Warmia and Mazury in Poland; Adam Nowakowski and Barbara Lukomska of the Mossakowski Medical Research Center in Poland; Jiadi Xu of the Kennedy Krieger Institute; and Moussa Chehade and Philippe Gailloud of the Johns Hopkins University.
The study was funded by the National Institute of Neurological Disorders and Stroke (grant numbers NS076573, NS045062, NS081544), the Maryland Stem Cell Research Fund, the Department of Defense (grant number PT120368), the Polish National Science Centre (grant number NCN 2012/07/B/NZ4/01427), the National Centre for Research and Development, and a Mobility Plus Fellowship from the Polish Ministry of Science and Higher Education.
Marcus Povey: Ran a successful first full test of my Flickr to @withknown photo and video import tool (http:/
@sillygwailo Okay, I thought you might know some trick I didn't! That line is more about reading and the use of timeshifting there is probably too subtle. Timeshifting is usually more frequently applied to live video/audio In particular, I've been thinking a lot about reading; I was apparently capturing the zeitgeist when I coincidentally posted this yesterday: http:/
Watched Limitless S1 | E20 "Hi, My Name Is Rebecca Harris" - CBS.com http:/